Delete all your products in Magento
If you don't know what you are doing don't do this. It will completely ruin your site. You will have no products left. Always make a backup!
This is tested on 1.6 +
Vern has pointed out I need to remove products and categories, I have posted his update
SET FOREIGN_KEY_CHECKS = 0;
TRUNCATE TABLE `core_url_rewrite`;
TRUNCATE TABLE `catalog_product_relation`;
TRUNCATE TABLE `catalog_category_entity`;
TRUNCATE TABLE `catalog_category_entity_datetime`;
TRUNCATE TABLE `catalog_category_entity_decimal`;
TRUNCATE TABLE `catalog_category_entity_int`;
TRUNCATE TABLE `catalog_category_entity_text`;
TRUNCATE TABLE `catalog_category_entity_varchar`;
TRUNCATE TABLE `catalog_category_product`;
TRUNCATE TABLE `catalog_category_product_index`;
INSERT INTO `catalog_category_entity`(`entity_id`,`entity_type_id`,`attribute_set_id`,`parent_id`,`created_at`,`updated_at`,`path`,`position`,`level`,`children_count`) VALUES (1,3,0,0,'0000-00-00 00:00:00','2009-02-20 00:25:34','1',1,0,1),(2,3,3,0,'2009-02-20 00:25:34','2009-02-20 00:25:34','1/2',1,1,0);
INSERT INTO `catalog_category_entity_int`(`value_id`,`entity_type_id`,`attribute_id`,`store_id`,`entity_id`,`value`) VALUES (1,3,34,0,2,1),(2,3,34,1,2,1);
INSERT INTO `catalog_category_entity_varchar`(`value_id`,`entity_type_id`,`attribute_id`,`store_id`,`entity_id`,`value`) VALUES
(1,3,33,0,1,'Root Catalog'),
(2,3,35,0,1,'root-catalog'),
(3,3,33,0,2,'Default Category'),
(4,3,41,0,2,'PRODUCTS'),
(5,3,35,0,2,'default-category');
TRUNCATE TABLE `catalog_product_bundle_option`;
TRUNCATE TABLE `catalog_product_bundle_option_value`;
TRUNCATE TABLE `catalog_product_bundle_selection`;
TRUNCATE TABLE `catalog_product_entity_datetime`;
TRUNCATE TABLE `catalog_product_entity_decimal`;
TRUNCATE TABLE `catalog_product_entity_gallery`;
TRUNCATE TABLE `catalog_product_entity_int`;
TRUNCATE TABLE `catalog_product_entity_media_gallery`;
TRUNCATE TABLE `catalog_product_entity_media_gallery_value`;
TRUNCATE TABLE `catalog_product_entity_text`;
TRUNCATE TABLE `catalog_product_entity_tier_price`;
TRUNCATE TABLE `catalog_product_entity_varchar`;
TRUNCATE TABLE `catalog_product_link`;
TRUNCATE TABLE `catalog_product_link_attribute`;
TRUNCATE TABLE `catalog_product_link_attribute_decimal`;
TRUNCATE TABLE `catalog_product_link_attribute_int`;
TRUNCATE TABLE `catalog_product_link_attribute_varchar`;
TRUNCATE TABLE `catalog_product_link_type`;
TRUNCATE TABLE `catalog_product_option`;
TRUNCATE TABLE `catalog_product_option_price`;
TRUNCATE TABLE `catalog_product_option_title`;
TRUNCATE TABLE `catalog_product_option_type_price`;
TRUNCATE TABLE `catalog_product_option_type_title`;
TRUNCATE TABLE `catalog_product_option_type_value`;
TRUNCATE TABLE `catalog_product_super_attribute_label`;
TRUNCATE TABLE `catalog_product_super_attribute_pricing`;
TRUNCATE TABLE `catalog_product_super_attribute`;
TRUNCATE TABLE `catalog_product_super_link`;
TRUNCATE TABLE `catalog_product_enabled_index`;
TRUNCATE TABLE `catalog_product_website`;
TRUNCATE TABLE `catalog_category_product_index`;
TRUNCATE TABLE `catalog_category_product`;
TRUNCATE TABLE `cataloginventory_stock_item`;
TRUNCATE TABLE `cataloginventory_stock_status`;
TRUNCATE TABLE `cataloginventory_stock`;
TRUNCATE TABLE `catalog_compare_item`;
TRUNCATE TABLE `adminnotification_inbox`;
TRUNCATE TABLE `index_event`;
TRUNCATE TABLE `index_process_event`;
TRUNCATE TABLE `log_url_info`;
TRUNCATE TABLE `log_url`;
TRUNCATE TABLE `log_visitor`;
TRUNCATE TABLE `log_visitor_info`;
TRUNCATE TABLE `report_viewed_product_index`;
TRUNCATE TABLE `report_event`;
DELETE FROM `eav_attribute_option` WHERE attribute_id = 70;
DELETE `eav_attribute_option_value`.* FROM `eav_attribute_option_value` LEFT JOIN `eav_attribute_option` USING (`option_id`) WHERE `eav_attribute_option`.`option_id` IS NULL;
INSERT INTO `catalog_product_link_type`(`link_type_id`,`code`) VALUES (1,'relation'),(2,'bundle'),(3,'super'),(4,'up_sell'),(5,'cross_sell');
INSERT INTO `catalog_product_link_attribute`(`product_link_attribute_id`,`link_type_id`,`product_link_attribute_code`,`data_type`) VALUES (1,2,'qty','decimal'),(2,1,'position','int'),(3,4,'position','int'),(4,5,'position','int'),(6,1,'qty','decimal'),(7,3,'position','int'),(8,3,'qty','decimal');
INSERT INTO `cataloginventory_stock`(`stock_id`,`stock_name`) VALUES (1,'Default');
TRUNCATE TABLE `catalog_product_entity`;
SET FOREIGN_KEY_CHECKS = 1;